A comparative analysis of odontogenic maxillofacial infections in diabetic and nondiabetic patients: an institutional study
Kamat Rahul D., Dhupar Vikas, Akkara Francis, Shetye Omkar,
소속 상세정보
( Kamat Rahul D. ) - Rajiv Gandhi Medical Complex Goa Dental College and Hospital Department of Oral and Maxillofacial Surgery
( Dhupar Vikas ) - Rajiv Gandhi Medical Complex Goa Dental College and Hospital Department of Oral and Maxillofacial Surgery
( Akkara Francis ) - Rajiv Gandhi Medical Complex Goa Dental College and Hospital Department of Oral and Maxillofacial Surgery
( Shetye Omkar ) - Rajiv Gandhi Medical Complex Goa Dental College and Hospital Department of Oral and Maxillofacial Surgery
KMID : 0355620150410040176
Abstract
Objectives: The increased prevalence of antibiotic resistance is an outcome of evolution. Most patients presenting with odontogenic space infections also have associated systemic co-morbidities such as diabetes mellitus resulting in impaired host defense. The present study aims to compare the odontogenic spaces involved, antibiotic susceptibility of microorganisms, length of hospital stay, and the influenceof systemic comorbidities on treatment outcome in diabetic patients.
Materials and Methods: A 2-year prospective study from January 2012 to January 2014 was conducted on patients with odontogenic maxillofacial space infections. The patients were divided into two groups based on their glycemic levels. The data were compiled and statistically analyzed.
Results: A total of 188 patients were included in the study that underwent surgical incision and drainage, removal of infection source, specimen collection for culture-sensitivity, and evaluation of diabetic status. Sixty-one out of 188 patients were found to be diabetic. The submandibular space was the most commonly involved space, and the most prevalent microorganism was Klebsiella pneumoniae in diabetics and group D Streptococcus in the nondiabetic group.
Conclusion: The submandibular space was found to be the most commonly involved space, irrespective of glycemic control. Empiric antibiotic therapy with amoxicillin plus clavulanic acid combined with metronidazole with optimal glycemic control and surgical drainage of infection led to resolution of infection in diabetic as well as nondiabetic patients. The average length of hospital stay was found to be relatively longer in diabetic individuals.
키워드
Comparative analysis; Odontogenic; Diabetics; Infection
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